Atypia in fine needle aspirates of breast lesions
نویسندگان
چکیده
منابع مشابه
Atypia in fine needle aspirates of breast lesions.
BACKGROUND The atypical category is controversial in fine needle aspiration cytology (FNAC) of the breast; most are benign, but a significant number are malignant. To date, no morphological criterion has been found to be consistent in predicting malignancy. AIMS To evaluate specific cytological parameters and assess their usefulness in predicting histological outcome in a cohort of atypical b...
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Thirty six fine needle aspirates from various types of benign breast lesions were examined by electron microscopy and correlated with their cytological appearances. In all cases the parenchyma consisted of clumps of cohesive cells with the ultrastructural features of epithelial cells. In many cases, particularly from fibroadenomas, the parenchyma consisted of single layers of polarised epitheli...
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Methods to determine individualized breast cancer risk lack sufficient sensitivity to select women most likely to benefit from preventive strategies. Alterations in DNA methylation occur early in breast cancer. We hypothesized that cancer-specific methylation markers could enhance breast cancer risk assessment. We evaluated 380 women without a history of breast cancer. We determined their menop...
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The goal of this work is to determine the accuracy of computer-based image analysis in diagnosing breast fine-needle aspirates (FNA). On 192 FNAs, the computerbased diagnostic accuracy was 97.9%. This is consistent with the 97.5% accuracy projected by machine learning methods during the initial training in 1994 with 569 FNAs. One of the attributes of this system is the rendering of a value that...
متن کاملConcordance Rate between Fine Needle Aspiration Biopsy and Core Needle Biopsy in Breast Lesions
Background and Objectives:Breast cancer is the most common cancer among women worldwide. Fine needle aspiration biopsy (FNAB) is one of the methods of breast biopsy which is fast, easy and cost effective. The aim of this study was to evaluate the concordance rate between pathologic results of sonography or stereotaxy guided FNAB and guided core needle biopsy (CNB) in the evaluation of breast le...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 2010
ISSN: 0021-9746
DOI: 10.1136/jcp.2010.084699